Miguel A. Martinez Gutierrez ; Igor F. P. da Silva; Henrique F. Goulart; Antônio E. G. Santana
Obtaining oil from urucum seeds by ultrasound-assisted extraction, Soxhlet, and steam distillation methods, characterization, and quantification.
Neilyane de Paula Fernandes; Fábio do Nascimento Ávila ; Késya Amanda D. Rocha
; Pedro B. de Mâcedo Carneiro
;
Greyce L. Sasahara ; Flavia A. Santos
; Edilberto R. Silveira
; Otília Deusdenia L. Pessoa
The chemical investigation of the ethyl acetate extract from the brown seaweed Dictyota mertensii led to the isolation of prenylated guaiane and dolabellane diterpenes.
Brenda R. C. Leocadio ; Taynara S. Vale; Felipe M. A. da Silva
; João V. C. O. Santos; Sergio M. Nunomura
; André C. de Oliveira; Ingrity S. C. Sá; Rosemary A. Roque; Ana Paula A. Castro; Magno P. Muniz
; Rita C. S. Nunomura
cis-Piplartine, piplartine and 4,5-dihydropiperlongumine isolated from leaves of Piper tuberculatum were active against Aedes aegypti larvae and have acetylcholinesterase (AChE) inhibitory activity.
Lucas Antônio F. de Almeida; Felipe Moura A. da Silva ; Bruna Ribeiro de Lima; Aline Bastos B. de Sousa;
Francinaldo A. da Silva Filho; Brenda R. C. Leocadio ; Ana Paula A. Castro; Rebeca dos S. França; Hector H. F. Koolen
;
Afonso D. L. de Souza; Maria Lúcia B. Pinheiro
Pallidine and other isoquinoline-derived alkaloids were tentatively identified in the trunk bark of U. rufescens through liquid chromatography coupled to tandem mass spectrometry analysis (LC-MS/MS) and fragmentation pattern analysis.
Davi S. Oliveira; Priscila B. A. de Souza; Luiz Henrique K. Queiroz-Junior; Denise O. Scoaris; Luana P. da Silva;
Claudete C. do Nascimento; Maria da Paz Lima
The modified flavonoids known as peltogynoids extracted from the wood residues of Peltogyne catingae Ducke ("roxinho") presented antifungal properties against Sporothrix schenckii and S. brasiliensis that cause feline sporotrichosis.
Thiago R. F. BastosI; Telma Leda G. de LemosI; Raimundo Braz FilhoII,III; Aluísio Marques da FonsecaIV;
Francisco J. Queiroz MonteI,*
Novel imides were synthesized from (E)-2,3-dihydro-1H-inden-1-one oxime via Beckmann-like rearrangement with nucleophilic catalysts. Molecular docking indicated that derivatives 5i, 5g, and 5h showed promising acetylcholinesterase inhibition compared to galantamine.
Kathia Raquel Murillo PadillaI; Rayanne Priscila Vieira da ConceiçãoI; Gisele da Costa RamosI; Luana Cardoso de OliveiraII,
José Edson de Sousa SiqueiraI; Mayra Suelen da Silva PinheiroIII; Patrícia Santana Barbosa MarinhoI,;
Andrey Moacir do Rosario MarinhoI,II,*
Tyrosol derivative compounds isolated from Actinomucor elegan fungus show good antimicrobial activity against Xanthomonas bacteria which causes bacterial spots in passion fruit.
Anauara Lima e SilvaI; Thiago A. M. BritoI; Maria de Fátima AgraII; Marcelo S. da SilvaI; Josean F. TavaresI,*
Saponins and glycosylated steroidal alkaloids were isolated from the hydroalcoholic extract of aerial parts of Solanum jabrense Agra & M.Nee, identified and characterized by nuclear magnetic resonance (NMR), infrared spectroscopy (IR), mass spectrometry (MS) and optical rotation.
Pedro H. DamadaI,*; Pedro H. O. SantiagoII
; Javier EllenaII; André L. M. PortoI
The graphic shows Penicillium citrinum CBMAI 1186 reducing α,β-unsaturated ketones to γ,δ-unsaturated ketones at 32 ºC and 135 rpm. This demonstrates the regioselective and chemoselective efficiency of the strain, highlighting its potential as a biocatalyst.
Eliane O. SilvaI,*; Herbert J. DiasII,III; Anderson R. M. OliveiraIII; Antônio E. M. CrottiIII
Methyl trans-ferulate was converted into the dihydrobenzofuran neolignan trans-dehydroferulate dimethyl ester with good enantioselectivity using an advantageous approach based on Trametes versicolor FC.
Renata Rodrigues da Silva RobainaI,*; Gabriela DinisII; Lucas Silva AbreuII
; Raimundo Braz-FilhoI,III; Ivo José Curcino VieiraI
The phytochemical study of Trichilia hirta Linneaus (Meliaceae) seeds resulted in the isolation and identification of a new limonoid named Hirtinol A, in addition to a mixture of 21α-melianone and 21β-melianone, and the glycoside schumaniofioside A.
Nathalia F. QuintilianoI,II; Sávio R. SoaresII; Miriam UemiI; Guilherme M. AntarIII; Patricia SartorelliII; Andre G. TemponeIV;
João Henrique G. LagoI,*
Bioactive hexane extract from leaves of Piper crassinervium was subjected to a bioactivity-guided fractionation to afford five metabolites (1-5). Compound 5 is previously undescribed while compounds 1, 2 and 4 are being described for the first time in P. crassinervium. Compounds 1-5 were evaluated against trypomastigote forms of parasite Trypanosoma cruzi whereas their toxicity was evaluated against NCTC cells.
Brenda K. M. SousaI; Talita L. N. GonçalvesI; Lívia M. DutraI; Victória L. A. SantosII; Emmanoel Vilaça CostaIII
;
Agnaldo R. M. ChavesIV, José M. PintoIV, Marcelo F. R. SilvaV; Yuri M. NascimentoV; Josean F. TavaresV; Marcelo S. SilvaV;
Jackson R. G. S. AlmeidaI,*
Seven compounds, belonging to the flavonoid, phenylpropanoid and chromone classes, were isolated from the leaves of Eriodictyon californicum. Among the isolated compounds, ethyl cinnamate (6) and 5-hydroxy-7-methoxychromone (7) are being reported for the first time in E. californicum and in the Boraginaceae family.
Alice M. S. de Almeida; Tchiara M. A. Tenório; Lucas V. B. Rodrigues; Carolina A. de Araujo; Claudio A. G. da Camara*;
Marcilio M. de Moraes
The analysis of essential oils from three Thunbergia species revealed differences in their chemical profiles, but all contained sesquiterpenes as the predominant compounds. The oil from T. erecta demonstrated the highest efficacy in the DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid), AChE (acetylcholinesterase), and BuChE (butyrylcholinesterase) assays.
Yan R. RoblesI; Ricardo VessecchiI; Ivo J. C. VieiraII; Raimundo Braz-FilhoII,III,#; Antonio E. M. CrottiI,*
The fragmentation of deprotonated aspidospermine, aspidocarpine, demethoxypalosine, and aspidolimine was investigated in this work using negative electrospray ionization tandem mass spectrometry.
Thalya S. R. NogueiraI,*; Thiago C. SardouII; Julio Cesar Thurler JúniorII; Gabriela DinisIII; Vinícius D'avila B. PascoalII;
Lucas S. AbreuIII; Raimundo Braz FilhoI,IV; Aislan C. R. F. PascoalII; Ivo José C. VieiraI
Tabernaemontana hystrix (Apocynaceae) root bark showed antiproliferative potential against the HeLa cell line. Six alkaloids were isolated from EtOAc or BuOH fractions. Compounds 3 and 4 are being reported for the first time in the species, and compound 6 is new in the literature.
Janderson Barbosa Leite de AlbuquerqueI; Otemberg Souza ChavesI; Wallace Amorim Machado de QueirozI;
Bárbara Fernandes Araújo RodriguesII; Diégina Araújo FernandesIII; Fábio Correia SampaioIV; Maria de Fátima AgraV; Maria de Fátima Vanderlei de SouzaI,II,*
A phytochemical investigation of the aerial parts of Pavonia malacophylla resulted in the isolation and identification of eighteen compounds, revealing antimicrobial potential in its extract, fractions and isolated compounds.
Fábio G. de Souza; Gabriel S. Crispim; Luana da C. Moreira; Cecilia V. Nunez*
Main databases used to search for articles about Remijia, and some of their biological activities and chemical substances.
Ricardo Vessecchi ; Pâmela R. R. Pereira; Leonardo Gobbo-Neto; Norberto Garcia-Cairasco; Norberto Peporine Lopes
Fragmentation from electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of caramboxin, a natural toxin, was explored using computational chemistry.
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