JBCS

The phytochemical study of Trichilia hirta Linneaus (Meliaceae) seeds resulted in the isolation and identification of a new limonoid named Hirtinol A, in addition to a mixture of 21α-melianone and 21β-melianone, and the glycoside schumaniofioside A.

Bioactive hexane extract from leaves of Piper crassinervium was subjected to a bioactivity-guided fractionation to afford five metabolites (1-5). Compound 5 is previously undescribed while compounds 1, 2 and 4 are being described for the first time in P. crassinervium. Compounds 1-5 were evaluated against trypomastigote forms of parasite Trypanosoma cruzi whereas their toxicity was evaluated against NCTC cells.

Schematic diagram of the procedure used. It consists of a glassy carbon electrode modified with graphene oxide and zinc stannate and a potentiostat/galvanostat coupled to a computer and can be used for the analysis of promethazine hydrochloride.

The study investigates thermoplastic starch (TPS) biocomposites with ucuuba fibers, focusing on the effect of buriti pulp oil. This oil improved the matrix, decreasing hydrophilicity and slightly increasing strength, while rheological and scanning electron microscopy (SEM) analyses confirmed better plasticization and enhanced thermal stability.

Seven compounds, belonging to the flavonoid, phenylpropanoid and chromone classes, were isolated from the leaves of Eriodictyon californicum. Among the isolated compounds, ethyl cinnamate (6) and 5-hydroxy-7-methoxychromone (7) are being reported for the first time in E. californicum and in the Boraginaceae family.

The analysis of essential oils from three Thunbergia species revealed differences in their chemical profiles, but all contained sesquiterpenes as the predominant compounds. The oil from T. erecta demonstrated the highest efficacy in the DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid), AChE (acetylcholinesterase), and BuChE (butyrylcholinesterase) assays.

The fragmentation of deprotonated aspidospermine, aspidocarpine, demethoxypalosine, and aspidolimine was investigated in this work using negative electrospray ionization tandem mass spectrometry.

Tabernaemontana hystrix (Apocynaceae) root bark showed antiproliferative potential against the HeLa cell line. Six alkaloids were isolated from EtOAc or BuOH fractions. Compounds 3 and 4 are being reported for the first time in the species, and compound 6 is new in the literature.

In the research, a bio adsorbent was produced as an alternative to textile wastewater treatment and could act as a tool for recycling dyes and saving water. This process would reduce the costs of dyeing fabrics by obtaining a new "ecological dye" for subsequent tanning.

The mangrove oyster Crassostrea brasiliana effectively monitored metal contamination in the Paciência River estuary, showing bioaccumulation patterns influenced by salinity and pH. Chromium and zinc levels exceeded health standards, highlighting risks and the need for monitoring.

A phytochemical investigation of the aerial parts of Pavonia malacophylla resulted in the isolation and identification of eighteen compounds, revealing antimicrobial potential in its extract, fractions and isolated compounds.

The ash generated by the burning of eucalyptus firewood and rice husk waste, used in biodiesel production boilers, can be used to purify frying oil and methylated soybean biodiesel.

Obtention of the unique phase H-Nb2O5 through a simple calcination route and its structural characterization and preliminary electrochemical evaluation.

This graphical abstract illustrates a novel methodology for real-time LHV (lower heating value) prediction in petrochemical plants using Poisson regression. The approach optimizes combustion efficiency in cracking furnaces, reducing energy consumption and emissions.

Blends of poly(methyl methacrylate)/polystyrene (PMMA/PS) with octadecylamine (ODA) that act in the interfacial region of the mixture and increase the charge density through the formation of the aggregates.

The novel polymer PAMNC12 synergizes with viscoelastic surfactants (VESs) to form a dense network structure, endowing the fracturing fluid with excellent sand-carrying capacity, drag reduction, temperature and shear resistance, and low formation damage.

Radon and its progeny account for 50% of exposure from natural sources. This study developed a simulator for indoor Rn monitoring. A concentration of 3,200 ± 324 and 4,654 ± 467 Bq m^-3 was obtained with passive and active methods, respectively.

The study used two classical models to analyze the infrared (IR) absorption of NaCl. The reduced mass linear diatomic model (RMLDM) showed no activity in IR, while linear diatomic model (LDM) suggests weak IR absorption. LDM combines elements of classical and quantum physics to obtain accurate estimates for IR absorption.

In this study, a novel berberine derivative featuring a substituted o-diaminobenzene moiety at the 9-position, strategically linked via an oxadiazole and alkyl chain, was rationally designed and synthesized based on the structural framework of histone deacetylase 6 (HDAC6) inhibitors. To elucidate its therapeutic potential, a comprehensive evaluation was conducted, integrating molecular docking, molecular dynamics simulations, and cytotoxicity assays. These studies collectively aimed to assess its binding affinity, stability, and anticancer efficacy, positioning this derivative as a promising HDAC6 inhibitor with potential therapeutic implications.

The use of multivariate tools for calibration and exploratory analysis was promisingly combined with the standard addition to characterize the content of Fe³⁺ ions available in medicinal herbal teas through digital image colorimetry.

The image illustrates the extraction of a biosurfactant from Citrus reticulata to synthesize and stabilize silver nanoparticles (AgNPs), which were characterized and tested for toxicity and surfactant properties. The AgNPs showed antimicrobial activity, mainly against two bacteria.

Pharmaceutical contaminants found in the Sangão River indicate inefficiency in the water treatment system impacting the environment.

The use of bioprospecting makes it possible to identify plant species that produce essential oils containing valuable chemical compounds, with potential for commercial applications.

This study evaluated the effects of the concentrations of the cross-linking agent sodium trimetaphosphate (STMP), alkalizing agent (sodium sulfate, SS) and cassava starch on the physical, chemical and mechanical properties of films based on cross-linked cassava starch.

Chemistry has been revolutionized by the use of organic molecules as stereo selective catalysts. Experimental and computational studies clarified the reaction mechanisms. Now, statistical modeling has emerged as a powerful tool to fine-tune the selectivity of organocatalysts.

Main databases used to search for articles about Remijia, and some of their biological activities and chemical substances.

Integration between teaching, research and extension, pillars of the 1000 Future Scientists program, highlighting the importance of university extension in the articulation between academic knowledge and teaching through social practices.

This article presents the "Stereochemistry Race", a multilingual educational game used in a Team Game Tournament (TGT) to review stereochemistry. The study involved 85 students from institutions in Brazil and Italy who evaluated the game and their social and emotional interactions after its implementation. The data showed increased student engagement and interest compared to traditional review classes.

Hybrid educational activities, which combine digital games and low-cost materials, can be effective in motivating students in challenging subjects. This article presents one of these activities, which used digital games on stereochemistry and nomenclature of organic compounds, encouraging interaction and facilitating learning.

Oswaldo Sala played a pioneering role in the introduction and development of vibrational spectroscopy in Brazil and Latin America. His trajectory is here detailed, from his hiring by USP (IAG 1949) to the consolidation of his research group at IQUSP, from 1969 onwards.

Escalab open innovation program starting from a technological demand from industry and development of the solution with universities.

Berthelot and Afonso Celso: two outstanding examples of 19^th century denialists. This study examines persistent denialism extending from the beginning of the modern period to our own days, across various fields.