JBCS



12:31, ter jun 17

Acesso Aberto/TP



ARTIGOS RECENTES


Artigo

AMIDES ISOLATED FROM THE LEAVES OF Piper tuberculatum Jacq. (Piperaceae) WITH ACETYLCHOLINESTERASE INHIBITION AND LARVICIDAL ACTIVITY AGAINST Aedes aegypti

Brenda R. C. Leocadio ; Taynara S. Vale; Felipe M. A. da Silva ; João V. C. O. Santos; Sergio M. Nunomura ; André C. de Oliveira; Ingrity S. C. Sá; Rosemary A. Roque; Ana Paula A. Castro; Magno P. Muniz ; Rita C. S. Nunomura

cis-Piplartine, piplartine and 4,5-dihydropiperlongumine isolated from leaves of Piper tuberculatum were active against Aedes aegypti larvae and have acetylcholinesterase (AChE) inhibitory activity.

http://dx.doi.org/10.21577/0100-4042.20250162

Publicado online: junho 17, 2025
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Total access: 2

LC-MS/MS BASED DEREPLICATION OF ISOQUINOLINE-DERIVED ALKALOIDS FROM THE TRUNK BARK OF Unonopsis rufescens (Baill.) R.E.Fr. (Annonaceae)

Lucas Antônio F. de Almeida; Felipe Moura A. da Silva ; Bruna Ribeiro de Lima; Aline Bastos B. de Sousa;
Francinaldo A. da Silva Filho; Brenda R. C. Leocadio ; Ana Paula A. Castro; Rebeca dos S. França; Hector H. F. Koolen ;
Afonso D. L. de Souza; Maria Lúcia B. Pinheiro

Pallidine and other isoquinoline-derived alkaloids were tentatively identified in the trunk bark of U. rufescens through liquid chromatography coupled to tandem mass spectrometry analysis (LC-MS/MS) and fragmentation pattern analysis.

http://dx.doi.org/10.21577/0100-4042.20250159

Publicado online: junho 17, 2025
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Total access: 3

PELTOGYNOIDS FROM Peltogyne catingae DUCKE AND THEIR ANTIFUNGAL POTENTIAL AGAINST Sporothrix spp.

Davi S. Oliveira; Priscila B. A. de Souza; Luiz Henrique K. Queiroz-Junior; Denise O. Scoaris; Luana P. da Silva;
Claudete C. do Nascimento; Maria da Paz Lima

The modified flavonoids known as peltogynoids extracted from the wood residues of Peltogyne catingae Ducke ("roxinho") presented antifungal properties against Sporothrix schenckii and S. brasiliensis that cause feline sporotrichosis.

http://dx.doi.org/10.21577/0100-4042.20250158

Publicado online: junho 16, 2025
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Total access: 27

EFFICIENT EXTRACTION OF 2'-FUCOSYLLACTOSE FROM HUMAN MILK: PARAMETER OPTIMIZATION WITH SURFACE RESPONSE

Elienae da Silva Gomes; Eloize Silva Alves; Patricia Daniele Silva Santos; Marcela de Souza Zangirolami; Oscar Oliveira Santos

Optimization of the extraction of the 2'-fucosyllactose from human milk, finding experimental conditions including optimizing solvent (water) and centrifugation time for safe and rapid extraction.

http://dx.doi.org/10.21577/0100-4042.20250157

Publicado online: junho 16, 2025
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Total access: 14

CLARIFICACIÓN DE VINAZAS PROVENIENTES DE LA INDUSTRIA DE LA "RAICILLA", MEDIANTE EL USO DE HIDROGELES

Maribel Arrizón Fregozo; Nestor García Ramírez; Jorge Alberto Cortes Ortega; Juan Carlos Sánchez Díaz

Scheme of the process of copper ion absorption, transformation into copper hydroxide entrapped in the hydrogel and the absorption of furfural, one of the organic compounds present in vinasse.

http://dx.doi.org/10.21577/0100-4042.20250156

Publicado online: junho 13, 2025
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Total access: 49

SYNTHESIS OF THE TiO2/g-C3N4 PHOTOCATALYST AND ITS PHOTOCATALYTIC PERFORMANCE FOR SELECTIVE OXIDATION OF ALCOHOLS

Shuangyan Meng; Bin Liu; Minglin Xie; Chaoxin Yun; Jin Qiang; Kaizhou He; Zhiwang Yang; Xiangqian Wang

A composite photocatalyst, xTCN, was synthesized using a simple one-step hydrothermal method, with H2O2 as the oxidant. This approach effectively reduced the bandgap energy and minimized the recombination of photogenerated carriers. The bandgap structure of g-C3N4 was modified by the incorporation of an O atom, improving the separation efficiency of the photogenerated electrons and holes.

http://dx.doi.org/10.21577/0100-4042.20250155

Publicado online: junho 13, 2025
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Total access: 23

1-INDANONE DERIVATIVES: A NOVEL ONE-POT APPROACH TO IMIDES VIA BECKMANN-LIKE REARRANGEMENT AND THEORETICAL INSIGHTS INTO THEIR INTERACTIONS WITH AChE ENZYME

Thiago R. F. Bastos; Telma Leda G. de Lemos; Raimundo Braz Filho; Aluísio Marques da Fonseca; Francisco J. Queiroz Monte

Novel imides were synthesized from (E)-2,3-dihydro-1H-inden-1-one oxime via Beckmann-like rearrangement with nucleophilic catalysts. Molecular docking indicated that derivatives 5i, 5g, and 5h showed promising acetylcholinesterase inhibition compared to galantamine.

http://dx.doi.org/10.21577/0100-4042.20250154

Publicado online: junho 11, 2025
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Total access: 41

ANTIMICROBIAL ACTIVITY OF COMPOUNDS ISOLATED FROM MANGROVE-DERIVED ENDOPHYTIC FUNGUS Actinomucor elegan AGAINST Xanthomonas axonopodis pv. passiflorae

Kathia Raquel Murillo Padilla; Rayanne Priscila Vieira da Conceição; Gisele da Costa Ramos; Luana Cardoso de Oliveira;
José Edson de Sousa Siqueira; Mayra Suelen da Silva Pinheiro; Patrícia Santana Barbosa Marinho;
Andrey Moacir do Rosario Marinho

Tyrosol derivative compounds isolated from Actinomucor elegan fungus show good antimicrobial activity against  Xanthomonas bacteria which causes bacterial spots in passion fruit.

http://dx.doi.org/10.21577/0100-4042.20250153

Publicado online: junho 10, 2025
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Total access: 73

GLICOSÍDEOS ESTEROIDAIS DE Solanum jabrense Agra & M.Nee

Anauara Lima e Silva; Thiago A. M. Brito; Maria de Fátima Agra; Marcelo S. da Silva; Josean F. Tavares

Saponins and glycosylated steroidal alkaloids were isolated from the hydroalcoholic extract of aerial parts of Solanum jabrense Agra & M.Nee, identified and characterized by nuclear magnetic resonance (NMR), infrared spectroscopy (IR), mass spectrometry (MS) and optical rotation.

http://dx.doi.org/10.21577/0100-4042.20250151

Publicado online: junho 10, 2025
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Total access: 47

REGIOSELECTIVE AND CHEMOSELECTIVE BIOCATALYTIC REDUCTION OF α,β,γ,δ-UNSATURATED KETONES BY MARINE-DERIVED FUNGUS Penicillium citrinum CBMAI 1186

Pedro H. Damada; Pedro H. O. Santiago; Javier Ellena; André L. M. Porto

The graphic shows Penicillium citrinum CBMAI 1186 reducing α,β-unsaturated ketones to γ,δ-unsaturated ketones at 32 ºC and 135 rpm. This demonstrates the regioselective and chemoselective efficiency of the strain, highlighting its potential as a biocatalyst.

http://dx.doi.org/10.21577/0100-4042.20250149

Publicado online: junho 3, 2025
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Total access: 87

Stereoselective oxidative coupling of methyl trans-ferulate to (±)-trans-dehydrodiferulate dimethyl ester by Trametes versicolor FC: an enantioselective green approach

Eliane O. SilvaI,*; Herbert J. DiasII,III; Anderson R. M. OliveiraIII; Antônio E. M. CrottiIII

Methyl trans-ferulate was converted into the dihydrobenzofuran neolignan trans-dehydroferulate dimethyl ester with good enantioselectivity using an advantageous approach based on Trametes versicolor FC.

http://dx.doi.org/10.21577/0100-4042.20250147

Publicado online: maio 30, 2025
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Total access: 87

Hirtinol A: a new limonoid from the seeds of Trichilia hirta Linneaus (Meliaceae)

Renata Rodrigues da Silva RobainaI,*; Gabriela DinisII; Lucas Silva AbreuII; Raimundo Braz-FilhoI,III; Ivo José Curcino VieiraI

The phytochemical study of Trichilia hirta Linneaus (Meliaceae) seeds resulted in the isolation and identification of a new limonoid named Hirtinol A, in addition to a mixture of 21α-melianone and 21β-melianone, and the glycoside schumaniofioside A.

http://dx.doi.org/10.21577/0100-4042.20250146

Publicado online: maio 21, 2025
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Total access: 125

Fenilpropanoides com ação anti-Trypanosoma cruzi isolados das folhas de Piper crassinervium (Piperaceae)

Nathalia F. QuintilianoI,II; Sávio R. SoaresII; Miriam UemiI; Guilherme M. AntarIII; Patricia SartorelliII; Andre G. TemponeIV;
João Henrique G. LagoI,*

Bioactive hexane extract from leaves of Piper crassinervium was subjected to a bioactivity-guided fractionation to afford five metabolites (1-5). Compound 5 is previously undescribed while compounds 1, 2 and 4 are being described for the first time in P. crassinervium. Compounds 1-5 were evaluated against trypomastigote forms of parasite Trypanosoma cruzi whereas their toxicity was evaluated against NCTC cells.

http://dx.doi.org/10.21577/0100-4042.20250145

Publicado online: maio 21, 2025
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Total access: 126

Sensor eletroquímico baseado em óxido de grafeno reduzido e estanato de zinco para determinação de prometazina

Andreza L. MoreiraI; Janevane S. de CastroI,II; Anderson V. ChavesI; Pierre B. A. FechineI; Pedro de Lima-NetoI,;
Francisco W. P. RibeiroIII; Paulo N. S. CascianoI; Adriana N. CorreiaI,*

Schematic diagram of the procedure used. It consists of a glassy carbon electrode modified with graphene oxide and zinc stannate and a potentiostat/galvanostat coupled to a computer and can be used for the analysis of promethazine hydrochloride.

http://dx.doi.org/10.21577/0100-4042.20250144

Publicado online: maio 20, 2025
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Total access: 112

Thermoplastic starch-ucuuba biocomposites: effect of buriti pulp oil on lignocellulosic fiber dispersion

Marcelo F. L. OliveiraI; Valdir F. Veiga-JuniorII; Marcia G. OliveiraI,; Fernanda Cristina F. BragaI,*

The study investigates thermoplastic starch (TPS) biocomposites with ucuuba fibers, focusing on the effect of buriti pulp oil. This oil improved the matrix, decreasing hydrophilicity and slightly increasing strength, while rheological and scanning electron microscopy (SEM) analyses confirmed better plasticization and enhanced thermal stability.

http://dx.doi.org/10.21577/0100-4042.20250142

Publicado online: maio 15, 2025
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Total access: 93

Chemical constituents from the leaves of Eriodictyon californicum (Hook. & Arn.) Torr. (Boraginaceae)

Brenda K. M. SousaI; Talita L. N. GonçalvesI; Lívia M. DutraI; Victória L. A. SantosII; Emmanoel Vilaça CostaIII;
Agnaldo R. M. ChavesIV, José M. PintoIV, Marcelo F. R. SilvaV; Yuri M. NascimentoV; Josean F. TavaresV; Marcelo S. SilvaV;
Jackson R. G. S. AlmeidaI,*

Seven compounds, belonging to the flavonoid, phenylpropanoid and chromone classes, were isolated from the leaves of Eriodictyon californicum. Among the isolated compounds, ethyl cinnamate (6) and 5-hydroxy-7-methoxychromone (7) are being reported for the first time in E. californicum and in the Boraginaceae family.

http://dx.doi.org/10.21577/0100-4042.20250140

Publicado online: maio 12, 2025
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Total access: 145

Chemical composition, antioxidant potential, and cholinesterase inhibitory activity of essential oils from three Thunbergia species growing wild in northeast Brazil

Alice M. S. de Almeida; Tchiara M. A. Tenório; Lucas V. B. Rodrigues; Carolina A. de Araujo; Claudio A. G. da Camara*;
Marcilio M. de Moraes

The analysis of essential oils from three Thunbergia species revealed differences in their chemical profiles, but all contained sesquiterpenes as the predominant compounds. The oil from T. erecta demonstrated the highest efficacy in the DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid), AChE (acetylcholinesterase), and BuChE (butyrylcholinesterase) assays.

http://dx.doi.org/10.21577/0100-4042.20250139

Publicado online: maio 9, 2025
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Total access: 153

Fragmentation of deprotonated plumeran indole alkaloids by electrospray ionization tandem mass spectrometry

Yan R. RoblesI; Ricardo VessecchiI; Ivo J. C. VieiraII; Raimundo Braz-FilhoII,III,#; Antonio E. M. CrottiI,*

The fragmentation of deprotonated aspidospermine, aspidocarpine, demethoxypalosine, and aspidolimine was investigated in this work using negative electrospray ionization tandem mass spectrometry.

http://dx.doi.org/10.21577/0100-4042.20250138

Publicado online: maio 9, 2025
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Total access: 136

A new alkaloid isolated from Tabernaemontana hystrix Steud. (Apocynaceae) and the antiproliferative potential of the root bark against human cervical cancer (HeLa)

Thalya S. R. NogueiraI,*; Thiago C. SardouII; Julio Cesar Thurler JúniorII; Gabriela DinisIII; Vinícius D'avila B. PascoalII;
Lucas S. AbreuIII; Raimundo Braz FilhoI,IV; Aislan C. R. F. PascoalII; Ivo José C. VieiraI

Tabernaemontana hystrix (Apocynaceae) root bark showed antiproliferative potential against the HeLa cell line. Six alkaloids were isolated from EtOAc or BuOH fractions. Compounds 3 and 4 are being reported for the first time in the species, and compound 6 is new in the literature.

http://dx.doi.org/10.21577/0100-4042.20250137

Publicado online: maio 6, 2025
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Total access: 190

Caracterização, análise quimiométrica e ensaios preliminares de adsorção de corantes têxteis em celulose bacteriana: uma tecnologia para tratamento de efluentes com proposta para desenvolvimento de economia sustentável

Rafaela J. L. Gouveia-RamosI,*; Alex S. MoraesII; Arthur L. Silva de AraújoII; Larissa M. S. GomesII; Thaís J. M. P. SoutoII; Beatriz S. SantosI; Otávio P. Santos JúniorIII; Romildo M. HolandaI; Gledson Luiz Pontes de AlmeidaI

In the research, a bio adsorbent was produced as an alternative to textile wastewater treatment and could act as a tool for recycling dyes and saving water. This process would reduce the costs of dyeing fabrics by obtaining a new "ecological dye" for subsequent tanning.

http://dx.doi.org/10.21577/0100-4042.20250136

Publicado online: maio 6, 2025
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Total access: 166

Phytochemical study from the aerial parts of Pavonia malacophylla (Malvaceae) and evaluation of its antimicrobial potential

Janderson Barbosa Leite de AlbuquerqueI; Otemberg Souza ChavesI; Wallace Amorim Machado de QueirozI;
Bárbara Fernandes Araújo RodriguesII; Diégina Araújo FernandesIII; Fábio Correia SampaioIV; Maria de Fátima AgraV; Maria de Fátima Vanderlei de SouzaI,II,*

A phytochemical investigation of the aerial parts of Pavonia malacophylla resulted in the isolation and identification of eighteen compounds, revealing antimicrobial potential in its extract, fractions and isolated compounds.

http://dx.doi.org/10.21577/0100-4042.20250134

Publicado online: maio 5, 2025
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Total access: 170


Revisão

Constituintes químicos e atividades biológicas de Remijia DC. (Rubiaceae): uma revisão

Fábio G. de Souza; Gabriel S. Crispim; Luana da C. Moreira; Cecilia V. Nunez*

Main databases used to search for articles about Remijia, and some of their biological activities and chemical substances.

http://dx.doi.org/10.21577/0100-4042.20250120

Publicado online: abril 3, 2025
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Total access: 261


Nota Técnica

COLLISION-INDUCED DISSOCIATION IN ESI-MS/MS OF CARAMBOXIN ISOLATED FROM Averrhoa carambola: COMPUTATIONAL AND MASS SPECTROMETRY STUDIES

Ricardo Vessecchi ; Pâmela R. R. Pereira; Leonardo Gobbo-Neto; Norberto Garcia-Cairasco; Norberto Peporine Lopes

Fragmentation from electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of caramboxin, a natural toxin, was explored using computational chemistry.

http://dx.doi.org/10.21577/0100-4042.20250160

Publicado online: junho 17, 2025
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Total access: 1


Educação

UMA SIMULAÇÃO DE CASO PARA INVESTIGAÇÃO DE VESTÍGIOS: ANÁLISE DE ADULTERANTES DE COCAÍNA EM IMPRESSÕES DIGITAIS UTILIZANDO A TÉCNICA DO PÓ E ESPECTROMETRIA DE MASSAS

Paula F. Filoda ; Tais Poletti; Bruno N. da Rosa ; Caroline I. Silveira; Alexandre M. Machado; Jeanifer T. Camacho;
Samuel A. Pereira; Clarissa M. M. dos Santos ; Claudio M. P. Pereira

Chemical concepts behind fingerprints addressed through a forensic situation, in order to arouse students' interest and curiosity during teaching.

http://dx.doi.org/10.21577/0100-4042.20250161

Publicado online: junho 17, 2025
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Total access: 1

Integração entre ensino, pesquisa e extensão: impactos do programa 1000 futuros cientistas na educação básica

Janaína P. Silva; Juliana A. S. Oliveira; Wladmir T. Silva; Natália R. S. Araujo; Rita C. O. Sebastião*

Integration between teaching, research and extension, pillars of the 1000 Future Scientists program, highlighting the importance of university extension in the articulation between academic knowledge and teaching through social practices.

http://dx.doi.org/10.21577/0100-4042.20250143

Publicado online: maio 20, 2025
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Total access: 80


Assuntos Gerais

FURTOS DE FONTES DE RADIAÇÃO E SEUS IMPACTOS: APLICAÇÃO DE CONCEITOS DE RADIOQUÍMICA/ QUÍMICA NUCLEAR E SEUS DESDOBRAMENTOS PARA A SOCIEDADE

Hector H. S. Medrado; Rodrigo G. de Souza Gois; Gildo R. S. Ferreira; Carlos Alberto de Carvalho Filho

Radioactive sources are widely used in modern society but are not widely known by the lay public. Unfortunately, these materials can be stolen and can cause serious problems to society. Assessing this kind of event is only possible if nuclear chemistry and radiochemistry concepts are recognized.

http://dx.doi.org/10.21577/0100-4042.20250150

Publicado online: junho 4, 2025
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Total access: 38

Perfil dos jovens doutores em química no Brasil: desafios, disparidades e perspectivas

Helena Mannochio-RussoI,*; Fábio G. DeloloII; Rayane C. F. SilvaII; Francisco L. F. da SilvaIII; Eduarda A. MoreiraIV; Vanessa NascimentoV; Rodolfo G. FiorotV; Irlon M. FerreiraVI; Juliana C. ThomasVII; Wilhan D. G. NunesI; Alan C. PilonVIII; Romeu C. Rocha-FilhoIX

Mapping the landscape of early-career researchers in chemistry across Brazil, highlighting demographic trends, research productivity, and challenges.

http://dx.doi.org/10.21577/0100-4042.20250148

Publicado online: maio 30, 2025
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Total access: 213

30 Anos das tabelas periódicas da SBQ: cursos passados e estado atual

Ana Paula de Lima BatistaI,#,*; Antonio Gustavo Sampaio de Oliveira-FilhoII,#,*; Romeu C. Rocha-FilhoI,#,*;
Yuri Alexandre AotoIII,IV,#,*

Overlay of the different formats (2025 versions) of the periodic table of the elements of the Brazilian Chemical Society: in the background, the front of the A4 format, overlaid in sequence by the poster format and the digital format.

http://dx.doi.org/10.21577/0100-4042.20250115

Publicado online: maio 30, 2025
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Total access: 122

Oswaldo Sala: cientista, educador e exemplo

Dalva L. A. de FariaI,II,*; Joel C. RubimIII; Marcia L. A. TemperiniI; Mauro C. C. RibeiroI; Paola CorioI; Paulo S. SantosI;
Rômulo A. AndoI; Yoshio KawanoI

Oswaldo Sala played a pioneering role in the introduction and development of vibrational spectroscopy in Brazil and Latin America. His trajectory is here detailed, from his hiring by USP (IAG 1949) to the consolidation of his research group at IQUSP, from 1969 onwards.

http://dx.doi.org/10.21577/0100-4042.20250141

Publicado online: maio 13, 2025
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Total access: 126

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