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2:27, qua mai 7

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ARTIGOS RECENTES


Artigo

A NEW ALKALOID ISOLATED FROM Tabernaemontana hystrix Steud. (Apocynaceae) AND THE ANTIPROLIFERATIVE POTENTIAL OF THE ROOT BARK AGAINST HUMAN CERVICAL CANCER (HeLa)

Thalya S. R. Nogueira; Thiago C. Sardou; Julio Cesar Thurler Júnior; Gabriela Dinis; Vinícius D'avila B. Pascoal; Lucas S. Abreu; Raimundo Braz Filho; Aislan C. R. F. Pascoal; Ivo José C. Vieira

Tabernaemontana hystrix (Apocynaceae) root bark showed antiproliferative potential against the HeLa cell line. Six alkaloids were isolated from EtOAc or BuOH fractions. Compounds 3 and 4 are being reported for the first time in the species, and compound 6 is new in the literature.

http://dx.doi.org/10.21577/0100-4042.20250137

Publicado online: maio 6, 2025
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Total access: 23

CARACTERIZAÇÃO, ANÁLISE QUIMIOMÉTRICA E ENSAIOS PRELIMINARES DE ADSORÇÃO DE CORANTES TÊXTEIS EM CELULOSE BACTERIANA: UMA TECNOLOGIA PARA TRATAMENTO DE EFLUENTES COM PROPOSTA PARA DESENVOLVIMENTO DE ECONOMIA SUSTENTÁVEL

Rafaela J. L. Gouveia-Ramos; Alex S. Moraes; Arthur L. Silva de Araújo; Larissa M. S. Gomes; Thaís J. M. P. Souto;
Beatriz S. Santos; Otávio P. Santos Júnior; Romildo M. Holanda; Gledson Luiz Pontes de Almeida

In the research, a bio adsorbent was produced as an alternative to textile wastewater treatment and could act as a tool for recycling dyes and saving water. This process would reduce the costs of dyeing fabrics by obtaining a new "ecological dye" for subsequent tanning.

http://dx.doi.org/10.21577/0100-4042.20250136

Publicado online: maio 6, 2025
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Total access: 22

MANGROVE OYSTERS (Crassostrea brasiliana) AS BIOMONITORS TO ASSESS METAL CONTAMINATION IN A MACRO-TIDAL ESTUARY ON THE AMAZONIAN EQUATORIAL COAST

Jacyara N. Correa; Thamires A. Torres; Daniel R. L. Brito; Samantha E. Martins; Carlos Eduardo de Rezende; Francisco J. S. Dias; Marco Valério J. Cutrim; Ricardo Luvizotto-Santos; Marianna B. Jorge

The mangrove oyster Crassostrea brasiliana effectively monitored metal contamination in the Paciência River estuary, showing bioaccumulation patterns influenced by salinity and pH. Chromium and zinc levels exceeded health standards, highlighting risks and the need for monitoring.

http://dx.doi.org/10.21577/0100-4042.20250135

Publicado online: maio 5, 2025
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Total access: 60

PHYTOCHEMICAL STUDY FROM THE AERIAL PARTS OF Pavonia malacophylla (MALVACEAE) AND EVALUATION OF ITS ANTIMICROBIAL POTENTIAL

Janderson Barbosa Leite de Albuquerque; Otemberg Souza Chaves; Wallace Amorim Machado de Queiroz; Bárbara Fernandes Araújo Rodrigues; Diégina Araújo Fernandes; Fábio Correia Sampaio; Maria de Fátima Agra; Maria de Fátima Vanderlei de Souza

A phytochemical investigation of the aerial parts of Pavonia malacophylla resulted in the isolation and identification of eighteen compounds, revealing antimicrobial potential in its extract, fractions and isolated compounds.

http://dx.doi.org/10.21577/0100-4042.20250134

Publicado online: maio 5, 2025
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Total access: 33

Sustainable use of boiler ash to purify biodiesel and waste frying oil: a proposal of circular economy

Rhalid AkelI; Fernanda S. LiraI; Vinicius C. LunaI; Matheus Z. MarquesII; Leonardo G. VasconcelosII; Marilza CastilhoI;
Adriana P. C. SiqueiraIII; Ailton J. TerezoI; Adriano B. de SiqueiraI,*

The ash generated by the burning of eucalyptus firewood and rice husk waste, used in biodiesel production boilers, can be used to purify frying oil and methylated soybean biodiesel.

http://dx.doi.org/10.21577/0100-4042.20250130

Publicado online: abril 25, 2025
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Total access: 106

Obtenção de fase única de pentóxido de nióbio por uma rota simples e sua caracterização

Michelle D. A. Lage*; Gabriel T. M. Alvarenga; Décio B. F. Neto; Gabriela C. Silva; Cássia R. Souza; Sônia D. F. Rocha

Obtention of the unique phase H-Nb2O5 through a simple calcination route and its structural characterization and preliminary electrochemical evaluation.

http://dx.doi.org/10.21577/0100-4042.20250131

Publicado online: abril 23, 2025
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Total access: 69

Metodologia de previsão em tempo real do PCI (Poder Calorífico Inferior) baseado na regressão de poisson para aplicação em sistemas de gás combustível de plantas petroquímicas

Lea S. dos SantosI,II,*; Rafael P. SoaresI

This graphical abstract illustrates a novel methodology for real-time LHV (lower heating value) prediction in petrochemical plants using Poisson regression. The approach optimizes combustion efficiency in cracking furnaces, reducing energy consumption and emissions.

http://dx.doi.org/10.21577/0100-4042.20250129

Publicado online: abril 16, 2025
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Total access: 171

Efeito do octadecilamina nas propriedades das blendas de poli(metacrilato de metila)/poliestireno

Jacqueline S. SousaI; Bruna de OliveiraII; Thaises B. S. de LimaII; Tiago F. A. SantosI; Fábio O. S. RibeiroIII;
Alyne R. de AraújoIII; Elmo S. AraújoII; Renata F. S. SantosII; Kátia A. S. AquinoII,*

Blends of poly(methyl methacrylate)/polystyrene (PMMA/PS) with octadecylamine (ODA) that act in the interfacial region of the mixture and increase the charge density through the formation of the aggregates.

http://dx.doi.org/10.21577/0100-4042.20250128

Publicado online: abril 15, 2025
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Total access: 83

Synergistic system study of hydrophobic associating water-soluble polymer and viscoelastic surfactant applied in fracturing fluid for unconventional oil and gas

Li Yan; Baolu Yu*; Yuewen Pan; Xuezhi Li; Zeyang Lou; Hongliang Tian

The novel polymer PAMNC12 synergizes with viscoelastic surfactants (VESs) to form a dense network structure, endowing the fracturing fluid with excellent sand-carrying capacity, drag reduction, temperature and shear resistance, and low formation damage.

http://dx.doi.org/10.21577/0100-4042.20250127

Publicado online: abril 14, 2025
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Total access: 94

CamInd α-Rn: a physical simulator for in vivo use

Cassya R. P. GuimarãesI; José A. dos Santos JúniorI,*; Eduardo E. N. de AraújoI; Romilton S. AmaralI; Isvânia M. S. S. LopesII; Artur P. CoutinhoIII; Josineide M. N. SantosI,III; Zahily H. FernándezI,III; Mariana B. C. F. BezerraI; Yasmin M. dos SantosI; Andrey J. I. A. R. AzevedoI; João Tadeu S. SantanaI

Radon and its progeny account for 50% of exposure from natural sources. This study developed a simulator for indoor Rn monitoring. A concentration of 3,200 ± 324 and 4,654 ± 467 Bq m-3 was obtained with passive and active methods, respectively.

http://dx.doi.org/10.21577/0100-4042.20250126

Publicado online: abril 11, 2025
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Total access: 126

Classical 1D linear models for infrared absorption and estimates for the vibrational amplitudes and energy of NaCI ionic compound

Jorge Corrêa de Araújo; Rosa María García Márquez*

The study used two classical models to analyze the infrared (IR) absorption of NaCl. The reduced mass linear diatomic model (RMLDM) showed no activity in IR, while linear diatomic model (LDM) suggests weak IR absorption. LDM combines elements of classical and quantum physics to obtain accurate estimates for IR absorption.

http://dx.doi.org/10.21577/0100-4042.20250122

Publicado online: abril 8, 2025
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Total access: 83

Synthesis, molecular docking, dynamics analysis studies, and cytotoxicityactivity evaluation of novel berberine derivative bearing oxadiazole and o-diaminobenzene moieties

Xiaofei JiangI,II; Yangming JiangIII,IV; Qing LiIII,IV; Lulin LiII and Daoping WangIII,IV,*

In this study, a novel berberine derivative featuring a substituted o-diaminobenzene moiety at the 9-position, strategically linked via an oxadiazole and alkyl chain, was rationally designed and synthesized based on the structural framework of histone deacetylase 6 (HDAC6) inhibitors. To elucidate its therapeutic potential, a comprehensive evaluation was conducted, integrating molecular docking, molecular dynamics simulations, and cytotoxicity assays. These studies collectively aimed to assess its binding affinity, stability, and anticancer efficacy, positioning this derivative as a promising HDAC6 inhibitor with potential therapeutic implications.

http://dx.doi.org/10.21577/0100-4042.20250121

Publicado online: abril 4, 2025
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Total access: 105

Uso da regressão Linear Múltipla Combinada Com Adição de Padrão (MLR-SA) e análise exploratória de imagens digitais na avaliação do perfil férrico em infusões de plantas medicinais

Bruno E. S. Costa*; Wallace H. C. Peres; James M. Silva; Carlos E. M. Braz; Vanessa N. Alves

The use of multivariate tools for calibration and exploratory analysis was promisingly combined with the standard addition to characterize the content of Fe3+ ions available in medicinal herbal teas through digital image colorimetry.

http://dx.doi.org/10.21577/0100-4042.20250119

Publicado online: abril 1, 2025
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Total access: 163

Plant surfactant as sustainable agent for silver nanoparticle synthesis and stabilization

Hozana S. FerreiraI; Júlio Cesar V. dos SantosI; Hugo M. MeiraII,III; Renata R. da SilvaIV; Fabíola Carolina G. de AlmeidaIII;
Leonie A. SarubboIII,V and Juliana M. de LunaIII,VI,*

The image illustrates the extraction of a biosurfactant from Citrus reticulata to synthesize and stabilize silver nanoparticles (AgNPs), which were characterized and tested for toxicity and surfactant properties. The AgNPs showed antimicrobial activity, mainly against two bacteria.

http://dx.doi.org/10.21577/0100-4042.20250117

Publicado online: março 31, 2025
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Total access: 98

Pharmaceutical contamination, water quality assessment and ecotoxicological evaluation of the surface waters of the Sangão River, Santa Catarina, Brazil

Michele D. FreitasI; Samira Leila BaldinII; Eduardo P. RicoII; James W. BarlowIII; Laíse D. S. RosaI; Silvia DalbóI;
Tânia Mara PizzolatoIV; Patrícia A. AmaralI,*

Pharmaceutical contaminants found in the Sangão River indicate inefficiency in the water treatment system impacting the environment.

http://dx.doi.org/10.21577/0100-4042.20250116

Publicado online: março 28, 2025
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Total access: 110

Bioprospecção de óleos essenciais com potencial para formulações farmacêuticas

Emanuelle O. Araújo*; Gabrielly S. Ferreira; Francine S. A. da Fonseca

The use of bioprospecting makes it possible to identify plant species that produce essential oils containing valuable chemical compounds, with potential for commercial applications.

http://dx.doi.org/10.21577/0100-4042.20250114

Publicado online: março 12, 2025
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Total access: 218

Investigations on the effect of sodium trimetaphosphate and sodium sulfate concentrations on the properties of cross-linked cassava starch films

Marisa Ferreira KarowI; Karine Laste MacagnanII; Mariane Igansi AlvesI; Júlia Borin FioravanteI; Rosane da Silva RodriguesI,III; Lígia FurlanIII; João Felipe Colosio de SouzaIV; Claire Tondo VendruscoloIV; Angelita da Silveira MoreiraI,II,III,*

This study evaluated the effects of the concentrations of the cross-linking agent sodium trimetaphosphate (STMP), alkalizing agent (sodium sulfate, SS) and cassava starch on the physical, chemical and mechanical properties of films based on cross-linked cassava starch.

http://dx.doi.org/10.21577/0100-4042.20250113

Publicado online: março 10, 2025
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Total access: 156


Revisão

Organocatálise assimétrica: evolução e aplicações computacionais em química orgânica sintética

Attilio Chiavegatti Neto; Giovanna S. Tâmega; Clarice A. D. Caiuby; Marco A. B. Ferreira*

Chemistry has been revolutionized by the use of organic molecules as stereo selective catalysts. Experimental and computational studies clarified the reaction mechanisms. Now, statistical modeling has emerged as a powerful tool to fine-tune the selectivity of organocatalysts.

http://dx.doi.org/10.21577/0100-4042.20250123

Publicado online: abril 8, 2025
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Total access: 84

Constituintes químicos e atividades biológicas de Remijia DC. (Rubiaceae): uma revisão

Fábio G. de Souza; Gabriel S. Crispim; Luana da C. Moreira; Cecilia V. Nunez*

Main databases used to search for articles about Remijia, and some of their biological activities and chemical substances.

http://dx.doi.org/10.21577/0100-4042.20250120

Publicado online: abril 3, 2025
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Total access: 160


Educação

Design of an educational gam e and its use in a team game tournament as a strategy to engage students in reviewing stereochemistry concepts

José Nunes da Silva JúniorI,*; Antonio José Melo Leite JuniorI; Renner César Silveira JucáI; Jean-Yves WinumII,III;
Andrea BassoIV; Chiara LambruschiniIV; Lara BianchiIV; Lisa MoniIV; Maria do Socorro Caldas TeotônioI

This article presents the "Stereochemistry Race", a multilingual educational game used in a Team Game Tournament (TGT) to review stereochemistry. The study involved 85 students from institutions in Brazil and Italy who evaluated the game and their social and emotional interactions after its implementation. The data showed increased student engagement and interest compared to traditional review classes.

http://dx.doi.org/10.21577/0100-4042.20250132

Publicado online: abril 25, 2025
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Total access: 72

Popping balloons: a fun activity to engage students in review of chemical nomenclature and stereochemistry by using educational games and low-cost materials

José Nunes da Silva JúniorI; Antonio José Melo Leite JuniorII; Renner César Silveira JucáI,*

Hybrid educational activities, which combine digital games and low-cost materials, can be effective in motivating students in challenging subjects. This article presents one of these activities, which used digital games on stereochemistry and nomenclature of organic compounds, encouraging interaction and facilitating learning.

http://dx.doi.org/10.21577/0100-4042.20250124

Publicado online: abril 8, 2025
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Total access: 111


Assuntos Gerais

Programas de inovação aberta na área de química: o caso do Mining Lab Beginnings-Nexa que conecta universidade-empresa estimulando o licenciamento de tecnologias e criação de startups

Saulo Luiz Sales Parreiras de RezendeI; Rafaela Leal PereiraII; Yasmim Rodrigues dos SantosII; Eduarda Rezende BarbosaII;
Rochel Montero LagoII,*; Fabiano Gomes Ferreira de PaulaII,*

Escalab open innovation program starting from a technological demand from industry and development of the solution with universities.

http://dx.doi.org/10.21577/0100-4042.20250133

Publicado online: abril 29, 2025
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Total access: 36

Negacionismo científico: prática antiga e persistente ao longo da história

Luiz C. A. Barbosa; Carlos A. L. Filgueiras*

Berthelot and Afonso Celso: two outstanding examples of 19th century denialists. This study examines persistent denialism extending from the beginning of the modern period to our own days, across various fields.

http://dx.doi.org/10.21577/0100-4042.20250125

Publicado online: abril 8, 2025
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Total access: 99

On-line version ISSN 1678-7064 Printed version ISSN 0100-4042
Química Nova
Publicações da Sociedade Brasileira de Química
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